bisphosphonates

  1. Common bone drug stops bone growth

    Osteoporosis med blocks bone growth

    A drug that could actually slow the new bone growth is the exact opposite of what I'd call an effective treatment for osteoporosis -- yet that's exactly what one leading medication may do, according to the latest research.

    And that means millions of women could be quietly suffering from the bone-wrecking side effects of their medication right now, and most of them don't even know it.

    In the new study of 40 postmenopausal women given either zoledronic acid (aka Reclast) or a placebo, the ones on the drug had higher levels of sclerostin, a biomarker that in essence stops new bone growth.

    On the plus side, the study finds the drug does in fact slow the thinning of the bone that marks the disease. But that's almost an afterthought here -- because if it's preventing new bone growth and bones from forming at the same time, then there's no chance your condition will ever truly improve.

    And there's every chance it could get worse.

    Besides, that's not the only risk of this medication.

    The FDA has warned of potential kidney damage linked to the use of this drug. It's also part of a class of medications known as bisphosphonates, and these drugs have been linked to esophageal cancer, necrosis of the jaw, and more than just blocking bone growth.

    Even worse, bisphosphonates can actually cause breaks in the very bones they're supposed to protect, especially after long-term use.

    Fortunately, there are safer and more natural ways to prevent, treat, and even reverse osteoporosis -- and it starts with understanding what causes the disease in the first place.

    Despite what you've heard, it's not aging. Not by itself, anyway. Osteoporosis is largely a disease of lifestyle -- one caused or worsened by poor diet and bad habits. In many cases, hormonal imbalances can also play a role.

    A holistic physician can test you for the possible causes of osteoporosis and get you started on a natural treatment.

  2. Osteoporosis drug Prolia linked to serious skin infections

    Bone drug is a skin disaster

    Sacrifice your skin to protect your bones? Not exactly what I'd call a good treatment for osteoporosis -- but if you're taking a common med given to women fighting this bone-thinning condition, you could be making that tradeoff right now.

    And you might not even know it until it's too late.

    A new analysis of FDA records finds that women who take the injectable osteoporosis drug denosumab -- aka Prolia -- have double or even triple the risk of serious skin infections, including cellulitis, angioedema, and pustular dermatitis.

    Researchers say a search through the FDA's Adverse Event Reporting System turned up 173 reports of skin-related problems linked to the drug -- including 41 reports involving 46 serious events (some people may have had more than one).

    In nine cases, the infections were so bad the patients required hospitalization.

    Remember, these are just the infections reported by doctors. Not every doctor files a report (even though they're supposed to) and some patients might not even tell their doctors about their side effects.

    The one bright spot here, if you can call it that, is that researchers say the risk only seems to apply to the dose used to treat osteoporosis -- and not the higher doses sometimes given for bone diseases caused by cancer.

    Skin infections aren't the only risks here, by the way -- this drug also brings a possibility of rashes and eczema as well as bladder infections, cataracts, back, joint and muscle pain, and constipation.

    Seems like there are no good drugs for osteoporosis. Not Prolia, and certainly not the bisphosphonates that are so popular right now.

    Those drugs can actually crack the very bones they're supposed to save.

    The best way to beat osteoporosis isn't with a drug that can cause even more harm -- it's by focusing on the lifestyle factors that can cause or worsen the disease in the first place.

    I had some tips on bone protection just a few weeks ago, and you can read them right here for free.

  3. How to beat osteoporosis

    The most important thing you need to know about osteoporosis is that this bone disease is not inevitable.
  4. Bad break for bone health

    Just six months after saying there's no link between osteoporosis meds and a higher risk of bone breaks, the FDA now says that osteoporosis meds have been linked to a higher risk of bone breaks.
  5. Bad to the bone: Osteoporosis meds linked to fractures

    Women taking osteoporosis meds may be getting the opposite of what they're looking for... because instead of protecting bones, the latest research finds that these drugs could be breaking them.

5 Item(s)