Effexor

  1. New concerns of suicidal ideation and antidepressants

    Antidepressants can lead to suicide in kids

    It's one of the most irresponsible studies I've ever seen -- because it could convince doctors and parents alike to make a decision with fatal consequences.

    And that's the decision to give antidepressant drugs to a child.

    You know the score with these meds. In many patients, they do nothing at all. But for some, especially kids and teens, the drugs can actually cause suicidal ideation. One drug, fluoxetine (Prozac), can even double the risk of suicidal ideation in children -- and that number comes right from the FDA's own data.

    So you have to question anyone who claims otherwise -- like Dr. Robert Gibbons, a University of Chicago researcher who says, in essence, forget those FDA numbers.

    Trust the numbers from him and his team instead -- because their new look at data on fluoxetine and venlafaxine (Effexor) finds absolutely no evidence the drugs increase the risk of suicide or suicidal ideation.

    But there's a huge problem with his study, and I'm not the only one who spotted it. Researchers from Harvard University noticed that Dr. Gibbons used a form of analysis that's open to bias.

    It's called mediation analysis, and even when it was used the study actually found that the drugs did increase the risk of suicide and suicidal ideation in kids -- but since it didn't reach statistical significance, at first glance it looks like a win for the meds.

    The FDA's numbers show otherwise.

    And that's not the only serious question here, because Dr. Robert Gibbons has served as an expert witness for the U.S. Department of Justice, and Wyeth in cases related to antidepressants and anticonvulsants and suicide.

    Wyeth is the original maker of Effexor, which is now part of Pfizer.

    I think that's a huge conflict of interest, so I'm not going to start recommending these drugs for kids based on this study. Besides, even if the drugs were safe for kids -- and they're clearly not -- there are much better ways to treat and beat depression.

    I know, because I've not only seen the science that backs these all-natural mood boosters, I also see the results in my own clinic every single day.

    And they work for adults as well as kids.

  2. Antidepressants fail another trial

    There's no two ways about it: When it comes to beating depression, that last thing you want is your doctor's first choice.

    Tell him you're down in the dumps, and he'll reach for his prescription pad -- but the dirty secret about the depression meds used by some 30 million Americans every year is that they just don't work.

    Too many people have already figured that out the hard way -- and now, a new study in the Journal of Clinical Psychiatry confirms it's not just them.

    It's the drugs.

    In this one, researchers put sertraline -- aka Zoloft -- up against both a placebo and a form of psychotherapy. Sixteen weeks later, and there was no statistical difference between any of the three groups.

    Some of the patients on Zoloft were even switched to another med, Effexor -- and still got no relief.

    This shouldn't surprise anyone, since studies have shown for years how even the most popular antidepressant drugs can't beat a placebo.

    But it did.

    "I was surprised by the results," confessed lead researcher Jacques P. Barber, dean of the Institute of Advanced Psychological Studies at Adelphi University in New York, according to Reuters. "They weren't what I'd expected."

    I'm not sure what Dr. Barber was expecting, since I tell you all the time about research in which antidepressants fall way short. A study just last month even found that not only do SSRIs get roughly the same response rate as the placebo, but they actually make the depression worse a full fifth of the time.

    That's not the only risk that comes from SSRIs -- and it's not even close to the worst risk. These drugs have been linked to everything from personality changes to sexual dysfunction to death, including death by suicide.

    But you don't have to put your life on the line for a treatment that doesn't work -- because there are real answers out there...answers that can change your life for the better if you're willing to look.

    In many cases, depression is a result of nutritional and hormonal imbalances -- something no antidepressant drug in the world can fix. A skilled naturopathic physician, however, can help you find the real source of your depression and correct it without meds.

    To find a doctor skilled in natural medicine, you may contact the American College for the Advancement in Medicine at www.acam.org, 949-309-3520, or 1-800-532-3688.

    For short-term relief while you look for that solution, you still don't have to turn to antidepressants. St. John's wort has matched or even beaten drugs in some studies, and the amino acid SAMe works so well it's often the first choice in Europe.

    You'll find both of them in any vitamin shop.

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